Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 10/20 | 0.65 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493786 | 0.91 | PRKCQ (0.79) | PRKCQNUAK1CDK1KDRLRRK2 | |
| SCHEMBL3494695 | 0.88 | PRKCQ (0.82) | PRKCQLRRK2SYK | |
| SCHEMBL3497136 | 0.88 | PRKCQ (0.49) | PRKCQCDK1LRRK2SYK | |
| SCHEMBL3496002 | 0.85 | SYK (0.47) | PRKCQNUAK1CDK1KDRLRRK2 | |
| SCHEMBL3493379 | 0.85 | PRKCQ (0.63) | PRKCQSYK | |
| SCHEMBL1740757 | 0.84 | PRKCQ (0.50) | PRKCQLRRK2SYKCSNK2A2CSNK2A1 | |
| SCHEMBL20752144 | 0.83 | PRKCQ (0.55) | PRKCQCDK1KDRLRRK2PLK1 | |
| SCHEMBL3495246 | 0.80 | PRKCQ (0.85) | PRKCQLRRK2SYK | |
| SCHEMBL3493139 | 0.79 | PRKCQ (0.84) | PRKCQLRRK2SYK | |
| SCHEMBL3494918 | 0.79 | PRKCQ (1.00) | PRKCQLRRK2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | claimed |
| US-8993585-B2 | Cyclic amine substituted pyrimidinediamines as PKC inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | PRKCH, PKD2, PRKCQ | PRKCQ 3/4885NUAK1 1042/4885CDK1 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.