SCHEMBL349666

SCHEMBL349666

CCOC(=O)Cc1ccc(OC)c(Oc2ccc([N+](=O)[O-])cc2CSc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.49
PPARA Q07869 2/20 0.49
ALDH1A1 P00352 8/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
HPGD P15428 2/20 0.47
HTT P42858 3/20 0.46
APOBEC3A P31941 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TP53 P04637 1/20 0.44
LMNA P02545 3/20 0.42
TTR P02766 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
LCK P06239 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349117 0.91 KMT2A (0.46) PPARGPPARAALDH1A1KMT2AMEN1
SCHEMBL349501 0.89 ALDH1A1 (0.52) PPARGPPARAALDH1A1KMT2AMEN1
SCHEMBL347672 0.86 CYP3A4 (0.53) ALDH1A1KMT2AMEN1HPGDHTT
SCHEMBL350012 0.85 HTT (0.44) ALDH1A1KMT2AMEN1HPGDHTT
SCHEMBL347866 0.85 PPARG (0.52) PPARGPPARAALDH1A1KMT2AMEN1
SCHEMBL348004 0.85 TTR (0.53) ALDH1A1KMT2AMEN1HTTMAPT
SCHEMBL2283432 0.85 KMT2A (0.48) ALDH1A1KMT2AMEN1HTTMAPT
SCHEMBL13521899 0.84 HTT (0.47) ALDH1A1KMT2AMEN1HTTMAPT
SCHEMBL347720 0.84 HTT (0.47) ALDH1A1KMT2AMEN1HTTMAPT
SCHEMBL347221 0.84 LCK (0.54) ALDH1A1KMT2AMEN1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4271879-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERIAL MM BOARD & PAPER GmbH (AT) 2023-11-08 EP claimed
WO-2022144176-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERIAL MM BOARD & PAPER GMBH (AT) 2022-07-07 WO claimed
EP-4023812-A1 METHOD FOR PRODUCING WOOD-BASED PRODUCTS MM BOARD & PAPER GmbH (AT) 2022-07-06 EP claimed
EP-4023813-A1 METHOD FOR PRODUCING WOOD-BASED PRODUCTS Technische Universität Wien (AT) 2022-07-06 EP claimed
EP-2181818-A2 Method for manufacturing wood fibre substances and wood fibre substances with lower emissions of volatile VOC IHD Institut für Holztechnologie Dresden gGmbH (DE) 2010-05-05 EP claimed
EP-4271879-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERIAL MM BOARD & PAPER GmbH (AT) 2023-11-08 EP disclosed
EP-4271880-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERAL MM BOARD & PAPER GmbH (AT) 2023-11-08 EP disclosed
WO-2022144377-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERAL MM BOARD & PAPER GMBH (AT) 2022-07-07 WO disclosed
WO-2022144176-A1 METHOD FOR PRODUCING PRODUCTS BASED ON WOOD AS A RAW MATERIAL MM BOARD & PAPER GMBH (AT) 2022-07-07 WO disclosed
EP-4023812-A1 METHOD FOR PRODUCING WOOD-BASED PRODUCTS MM BOARD & PAPER GmbH (AT) 2022-07-06 EP disclosed
EP-4023813-A1 METHOD FOR PRODUCING WOOD-BASED PRODUCTS Technische Universität Wien (AT) 2022-07-06 EP disclosed
US-8247602-B2 Antagonists of prostaglandin D2 receptors PANMIRA PHARMACEUTICALS, LLC (US) 2012-08-21 US disclosed
US-20110190227-A1 Antagonists of Prostaglandin D2 Receptors AMIRA PHARMACEUTICALS, INC. (US) 2011-08-04 US disclosed
US-20110190227-A1 Antagonists of Prostaglandin D2 Receptors AMIRA PHARMACEUTICALS, INC. (US) 2011-08-04 US disclosed
US-20110144160-A1 Antagonists of Prostaglandin D2 Receptors AMIRA PHARMACEUTICALS, INC. (US) 2011-06-16 US disclosed
EP-2307362-A2 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS Amira Pharmaceuticals, Inc. (US) 2011-04-13 EP disclosed
US-20100004331-A1 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-01-07 US disclosed
WO-2010003120-A2 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-01-07 WO disclosed
WO-2010003127-A2 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-01-07 WO disclosed
WO-2010003127-A2 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004331-A1 ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS PTGDR, PTGDR2, PTGER2 PPARG 35/4885PPARA 133/4885ALDH1A1 2185/4885
US-20110144160-A1 Antagonists of Prostaglandin D2 Receptors PTGDR, PTGDR2, PTGER2 PPARG 35/4885PPARA 133/4885ALDH1A1 2185/4885
US-20110190227-A1 Antagonists of Prostaglandin D2 Receptors PTGDR, PTGDR2, PTGER2 PPARG 24/4885PPARA 86/4885ALDH1A1 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.