⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633324 | 1.00 | — | — | |
| SCHEMBL15508385 | 1.00 | — | — | |
| SCHEMBL31352548 | 1.00 | — | — | |
| SCHEMBL491883 | 1.00 | — | — | |
| SCHEMBL4204733 | 1.00 | — | — | |
| SCHEMBL6182662 | 1.00 | — | — | |
| SCHEMBL92625 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6132910 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15519440 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL71659 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | claimed |
| US-8273743-B2 | N-(4-chloro-3-(quinoxalin-3-yl)phenyl)-3,5-dimethoxybenzamide; for treating malignancies | CURIS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| EP-1745041-B1 | QUINOXALINE INHIBITORS OF THE HEDGEHOG SIGNALLING PATHWAY | GENENTECH INC (US) | 2012-06-20 | — | — | EP | disclosed |
| US-20080261989-A1 | Quinoxaline Inhibitors of the Hedgehog Signalling | GENENTECH, INC. | 2008-10-23 | — | — | US | disclosed |
| EP-1745041-A2 | QUINOXALINE INHIBITORS OF THE HEDGEHOG SIGNALLING PATHWAY | Genentech, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| US-7098219-B2 | Quinolone derivatives | WOCKHART LIMITED (IN) | 2006-08-29 | — | — | US | disclosed |
| WO-2006078283-A2 | QUINOXALINE INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| EP-0548710-B1 | Glycol aldehyde and lactic acid derivatives, their preparation and their use as herbicides | BASF AG (DE) | 1996-10-16 | — | — | EP | disclosed |
| US-5326744-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| EP-0548710-A1 | Glycol aldehyde and lactic acid derivatives, their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1993-06-30 | — | — | EP | disclosed |