⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633324 | 1.00 | — | — | |
| SCHEMBL15508385 | 1.00 | — | — | |
| SCHEMBL3497544 | 1.00 | — | — | |
| SCHEMBL31352548 | 1.00 | — | — | |
| SCHEMBL4204733 | 1.00 | — | — | |
| SCHEMBL6182662 | 1.00 | — | — | |
| SCHEMBL92625 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6132910 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15519440 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL71659 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040934-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2013-02-14 | — | — | US | claimed |
| EP-2547684-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | University of Basel (CH) | 2013-01-23 | — | — | EP | claimed |
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | claimed |
| EP-1140924-B1 | PIPERAZINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2006-03-22 | — | — | EP | claimed |
| US-5733755-A | Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-t | INDUSTRIE CHIMICHE CAPPARO S.P.A. (IT) | 1998-03-31 | — | — | US | claimed |
| EP-0775683-A1 | Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-Tert-Butyl)-Phenyl-2-Methyl propylamine, systemic fungicides | INDUSTRIE CHIMICHE CAFFARO S.p.A. (IT) | 1997-05-28 | — | — | EP | claimed |
| JP-9188650-A | — | — | None | — | — | JP | disclosed |
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |
| US-20250320228-A1 | PYRIDO[3,2-D]PYRIMIDINES AS HPK1 INHIBITORS | MERCK PATENT GMBH (DE) | 2025-10-16 | — | — | US | disclosed |
| US-12441731-B2 | Pyrazolopyrimidine compounds and uses thereof | INCYTE CORPORATION (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250236608-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-07-24 | — | — | US | disclosed |
| US-20250214998-A1 | CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF | BIONOMICS LTD (AU) | 2025-07-03 | — | — | US | disclosed |
| US-5733755-A | Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-t | INDUSTRIE CHIMICHE CAPPARO S.P.A. (IT) | 1998-03-31 | — | — | US | disclosed |
| JP-H09188650-A | ENANTIOSELECTIVE SYNTHESIS OF CHIRAL DERIVATIVE OF SYSTEMIC GERMICIDE S-3-(4'-TERTIARY BUTYL)-PHENYL-2METHYL-PROPYLAMINE | IND CHIM CAFFARO SPA | 1997-07-22 | — | — | JP | disclosed |
| EP-0775683-A1 | Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-Tert-Butyl)-Phenyl-2-Methyl propylamine, systemic fungicides | INDUSTRIE CHIMICHE CAFFARO S.p.A. (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0775683-A1 | Method for the enantioselective synthesis of chiral derivatives of S-3-(4'-Tert-Butyl)-Phenyl-2-Methyl propylamine, systemic fungicides | INDUSTRIE CHIMICHE CAFFARO S.p.A. (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0091057-B1 | 5,6-DIHYDRO-11-ALKYLENE-MOPHANTRIDIN-6-ONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1986-06-11 | — | — | EP | disclosed |
| US-4477451-A | TREATMENT OF ULCERS | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-16 | — | — | US | disclosed |
| EP-0091057-A2 | 5,6-Dihydro-11-alkylene-mophantridin-6-ones, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1983-10-12 | — | — | EP | disclosed |