SCHEMBL3499359

SCHEMBL3499359

O=C(CBr)c1ccc2sccc2c1

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 4/20 0.65
WNT3A P56704 4/20 0.65
PTPN1 P18031 5/20 0.54
NAMPT P43490 1/20 0.45
GSK3B P49841 5/20 0.44
CYP2A6 P11509 2/20 0.43
MRGPRX4 Q96LA9 1/20 0.41
CHRNA7 P36544 1/20 0.40
HTR3A P46098 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6329466 0.83 CTNNB1 (0.65) CTNNB1WNT3ANAMPTCYP2A6MRGPRX4
SCHEMBL6327569 0.80 CTNNB1 (0.70) CTNNB1WNT3ANAMPTCYP2A6
SCHEMBL6329867 0.79 CTNNB1 (0.60) CTNNB1WNT3ANAMPTCYP2A6MRGPRX4
SCHEMBL15969221 0.79 CTNNB1 (1.00) CTNNB1WNT3ANAMPTMRGPRX4
SCHEMBL25570121 0.79 CTNNB1 (0.60) CTNNB1WNT3ANAMPTCYP2A6MRGPRX4
SCHEMBL30489890 0.78 CTNNB1 (0.63) CTNNB1WNT3ANAMPTCYP2A6MRGPRX4
SCHEMBL573187 0.78 CTNNB1 (0.63) CTNNB1WNT3ANAMPTCYP2A6MRGPRX4
SCHEMBL15980113 0.78 CTNNB1 (0.76) CTNNB1WNT3ANAMPTGSK3B
SCHEMBL15979975 0.78 CTNNB1 (0.76) CTNNB1WNT3APTPN1NAMPT
SCHEMBL11482012 0.77 PTPN1 (0.84) PTPN1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112359363-A Anti-corrosion sulfonate for metal surface treatment and application thereof 邓华斌 2021-02-12 CN claimed
CN-112267109-A Corrosion-resistant oxidation-resistant film forming material of metal surface treating agent 邓华斌 2021-01-26 CN claimed
CN-112267125-A Preparation method of environment-friendly metal surface treating agent 邓华斌 2021-01-26 CN claimed
CN-112251743-A Corrosion-resistant anti-oxidation metal protection film 邓华斌 2021-01-22 CN claimed
CN-112251759-A Antioxidant metal surface film forming additive 邓华斌 2021-01-22 CN claimed
CN-112176357-A Wax-removing, bacteriostatic and antioxidant additive of metal surface treating agent 邓华斌 2021-01-05 CN claimed
CN-110004451-B Environment-friendly metal surface treating agent and preparation method thereof 上海丰野表面处理剂有限公司 2020-12-08 CN claimed
CN-112359363-A Anti-corrosion sulfonate for metal surface treatment and application thereof 邓华斌 2021-02-12 CN disclosed
CN-112359363-A Anti-corrosion sulfonate for metal surface treatment and application thereof 邓华斌 2021-02-12 CN disclosed
CN-112267109-A Corrosion-resistant oxidation-resistant film forming material of metal surface treating agent 邓华斌 2021-01-26 CN disclosed
CN-112267125-A Preparation method of environment-friendly metal surface treating agent 邓华斌 2021-01-26 CN disclosed
CN-112267125-A Preparation method of environment-friendly metal surface treating agent 邓华斌 2021-01-26 CN disclosed
CN-112251759-A Antioxidant metal surface film forming additive 邓华斌 2021-01-22 CN disclosed
WO-2006020049-A2 ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN AMR TECHNOLOGY, INC. (US) 2006-02-23 WO disclosed
US-5872117-A TREATING CEREBROVASCULAR DEMENTIA, SENILE DEMENTIA, ALZHEIMER'S DEMENTIA, SEQUELAE OF ISCHEMIC ENCEPHALOPATHY AND CEREBRAL APOPLEXY TOYAMA CHEMICAL CO., LTD. (JP) 1999-02-16 US disclosed
US-5719150-A ALZHEIMER'S DISEASE TOYAMA CHEMICAL CO., LTD. (JP) 1998-02-17 US disclosed
US-5658904-A COGNITION ACTIVATORS; BRAIN DISORDERS; ALZHEIMER*S DISEASE TOYAMA CHEMICAL CO., LTD. (JP) 1997-08-19 US disclosed
US-5612381-A 1,2-ethanediol derivative and salt thereof process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1997-03-18 US disclosed
US-5472984-A 1,2-ethanediol derivative and salt thereof and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1995-12-05 US disclosed
US-5280032-A 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same TOYAMA CHEMICAL CO., LTD. (JP) 1994-01-18 US disclosed