Procodazole

Procodazole

SCHEMBL349966

O=C(O)CCc1nc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 1.00
KDM4E B2RXH2 2/20 0.68
PARP1 P09874 1/20 0.68
PARP2 Q9UGN5 1/20 0.68
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
MAPT P10636 1/20 0.65
APEX1 P27695 1/20 0.64
POLB P06746 1/20 0.64
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
PDE10A Q9Y233 1/20 0.60
GAA P10253 1/20 0.60
HTT P42858 1/20 0.60
PRKAG1 P54619 2/20 0.59
PRKAA2 P54646 2/20 0.59
PRKAB1 Q9Y478 2/20 0.59
ALDH1A1 P00352 1/20 0.59
PRKAA1 Q13131 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Procodazole SCHEMBL838841 1.00 CHRM1 (1.00) CHRM1KDM4EPARP1PARP2CYP1A2
Procodazole SCHEMBL29404024 1.00 CHRM1 (1.00) CHRM1KDM4EPARP1PARP2CYP1A2
Procodazole SCHEMBL5413283 0.95 CHRM1 (0.91) CHRM1KDM4EPARP1PARP2CYP1A2
SCHEMBL2017763 0.90 CHRM1 (0.82) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL7433457 0.89 CHRM1 (0.80) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL14565997 0.88 CHRM1 (0.78) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL12999426 0.86 GAA (0.75) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL4573158 0.85 CHRM1 (0.74) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL19368796 0.85 CHRM1 (0.74) CHRM1KDM4ECYP1A2CYP2C9MAPT
SCHEMBL5717769 0.85 CHRM1 (0.74) CHRM1KDM4ECYP1A2CYP2C9MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2361 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602049-A1 SOS1 INHIBITORS Bayer Aktiengesellschaft (DE) 2025-08-20 EP claimed
EP-4587439-A1 SULFONE-SUBSTITUTED PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER Bayer Aktiengesellschaft (DE) 2025-07-23 EP claimed
US-20250154170-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 US claimed
CN-119894893-A Sulfone substituted pyrido [3,4-D ] pyrimidine derivatives for the treatment of cancer 拜耳公司 2025-04-25 CN claimed
WO-2025021997-A1 NEW MAP4K1 INHIBITORS Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2025-01-30 WO claimed
WO-2025016899-A1 SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2025-01-23 WO claimed
EP-4476221-A1 FUSED PYRIMIDINES AS KRAS INHIBITORS Bayer Aktiengesellschaft (DE) 2024-12-18 EP claimed
WO-2024188937-A1 COMBINATIONS OF ATR KINASE INHIBITORS AND PARP INHIBITORS TO TREAT HYPER-PROLIFERATIVE CONDITIONS E.G. CANCER BAYER AKTIENGESELLSCHAFT (DE) 2024-09-19 WO claimed
US-20240247015-A1 PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-07-25 US claimed
WO-2024079252-A1 SOS1 INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
US-6110953-A Pharmaceutical composition for inhibiting the growth of cancers THE PROCTER & GAMBLE COMPANY (US) 2000-08-29 US claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-6090796-A Pharmaceutical composition for inhibiting the growth of cancers THE PROCTER & GAMBLE COMPANY (US) 2000-07-18 US claimed
US-5932604-A Pharmaceutical compositions for the treatment of viral infections THE PROCTER & GAMBLE COMPANY (US) 1999-08-03 US claimed
US-5908855-A ADMINISTERING FLUCONAZOLE WITH A POTENTIATOR (ESPECIALLY PROCODAZOLE). TREATMENT OF INFLUENZA. THE PROCTER & GAMBLE COMPANY (US) 1999-06-01 US claimed
US-5854231-A Pharmaceutical composition for inhibiting the growth of cancers THE PROCTER & GAMBLE COMPANY (US) 1998-12-29 US claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 WO claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed