Hydrochloric Acid

Hydrochloric Acid

SCHEMBL350109

OC[C@H]1O[C@@H](Oc2cc3c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc(O)cc3[o+]c2-c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O.[Cl-]

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.46
F2 P00734 1/20 0.81
DPP4 P27487 1/20 0.72
CD38 P28907 1/20 0.72
TYR P14679 1/20 0.52
SLC28A3 Q9HAS3 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 1/20 0.51
NPC1 O15118 1/20 0.48
ALDH1A2 O94788 1/20 0.48
ALDH2 P05091 1/20 0.48
ALDH1B1 P30837 1/20 0.48
RAB9A P51151 1/20 0.48
IL2 P60568 1/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 2/20 0.48
GAA P10253 1/20 0.48
G6PD P11413 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673925 0.99 F2 (0.83) F2DPP4CD38TYRSLC28A3
SCHEMBL29378039 0.99 F2 (0.83) F2DPP4CD38TYRSLC28A3
Hydrochloric Acid SCHEMBL316939 0.93 CD38 (0.83) F2DPP4CD38TYRSLC28A3
Hydrochloric Acid SCHEMBL29991538 0.93 CD38 (0.83) F2DPP4CD38TYRSLC28A3
SCHEMBL29517863 0.92 F2 (0.73) F2DPP4CD38TYRSLC28A3
Hydrochloric Acid SCHEMBL3437710 0.92 CD38 (0.82) F2DPP4CD38TYRSLC28A3
SCHEMBL347415 0.92 CD38 (0.85) F2DPP4CD38TYRSLC28A3
SCHEMBL29380925 0.92 CD38 (0.85) F2DPP4CD38TYRSLC28A3
SCHEMBL29816518 0.92 CD38 (0.85) F2DPP4CD38TYRSLC28A3
SCHEMBL316940 0.92 CD38 (0.85) F2DPP4CD38TYRSLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117357544-A Application of punicin in preparation of xanthine oxidase inhibitor 青岛大学 2024-01-09 CN claimed
CN-115671286-B Stereocomplex for delivery of anticancer agents 田德扬 2023-12-08 CN claimed
CN-117074573-A Method for discriminating fire baking degree of Wuyi cinnamon based on infrared and chromatographic methods of partial square method 福建省农业科学院茶叶研究所 2023-11-17 CN claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20230355769-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS Natural Extraction Systems, LLC (US) 2023-11-09 US claimed
US-20230338331-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS Natural Extraction Systems, LLC (US) 2023-10-26 US claimed
US-20230313246-A1 Application of Strain CH18 in Preparation of Anthocyanins and Other Flavonoid Compounds BEIJING INSTITUTE OF TECHNOLOGY (CN) 2023-10-05 US claimed
CN-115561966-B Chemical amplification type negative photosensitive polyimide coating adhesive and application thereof 明士(北京)新材料开发有限公司 2023-05-16 CN claimed
CN-114813985-A Method for constructing HPLC fingerprint of capsule for treating arthralgia due to cold and heat 长春英平药业有限公司 2022-07-29 CN claimed
CN-114712508-A Use of PDIA3 inhibitors in the prevention and treatment of CD4+ T cell dominated related diseases 华中科技大学同济医学院附属同济医院 2022-07-08 CN claimed
CN-101312662-A High-potency sweetener composition with antioxidant and compositions sweetened therewith COCA COLA CO (US) 2008-11-26 CN claimed
CN-100360115-C Molecular coating method of plant polyphenol kind substance XIE JUN (CN) 2008-01-09 CN claimed
CN-1839903-A Pharmaceutical composition containing glabrous sarcandra herb extract and its uses JIANGXI BOSHILIAN SCIENCE AND (CN) 2006-10-04 CN claimed
CN-1823730-A Molecular coating method of plant polyphenol kind substance XIE JUN (CN) 2006-08-30 CN claimed
EP-1212376-B1 SYNTHETIC VEGETAL MELANINS, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEM GHISALBERTI CARLO (BR) 2006-02-01 EP claimed
EP-1212376-A1 SYNTHETIC VEGETAL MELANINS, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEREOF Ghisalberti, Carlo (BR) 2002-06-12 EP claimed
WO-2002002066-A1 NAPHTHOMELANINS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS THEREOF GHISALBERTI CARLO (BR) 2002-01-10 WO claimed
WO-2001018125-A1 SYNTHETIC VEGETAL MELANINS, PROCESS FOR THEIR PRODUCTION AND COMPOSITIONS CONTAINING THEREOF GHISALBERTI CARLO (BR) 2001-03-15 WO claimed
EP-0496349-B1 Coating solution for preventing adhesion of polymer scale and method for its use SHINETSU CHEMICAL CO (JP) 1996-04-10 EP claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355769-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS CNR2, CNR1, UGT8 ACHE 3117/4885F2 50/4885DPP4 4789/4885
US-20230338331-A1 COMPOSITIONS, CONTAINERS, AND METHODS RELATED TO FLAVYLIUM EXCIPIENTS CNR2, CNR1, UGT8 ACHE 3117/4885F2 50/4885DPP4 4789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.