SCHEMBL3501337

SCHEMBL3501337

CN(C)c1ccc2c3c(cccc13)C(=O)NC2=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.69
▸ KMT2A Q03164 5/20 0.69
▸ POLB P06746 3/20 0.69
▸ USP2 O75604 4/20 0.57
▸ TDP1 Q9NUW8 4/20 0.57
▸ PARP1 P09874 2/20 0.57
▸ CASP1 P29466 2/20 0.57
▸ CASP7 P55210 2/20 0.57
▸ NPSR1 Q6W5P4 2/20 0.57
▸ MAPT P10636 2/20 0.57
▸ RGS12 O14924 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ THRB P10828 1/20 0.57
▸ CYP2C9 P11712 1/20 0.57
▸ APEX1 P27695 1/20 0.57
▸ BRCA1 P38398 1/20 0.57
▸ MTOR P42345 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ BLM P54132 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30831694 1.00 MEN1 (0.69) MEN1KMT2APOLBUSP2TDP1
SCHEMBL11332532 0.87 MEN1 (0.56) MEN1KMT2APOLBUSP2TDP1
SCHEMBL28085238 0.84 KMT2A (0.70) MEN1KMT2APOLBUSP2TDP1
SCHEMBL28114523 0.83 MEN1 (0.50) MEN1KMT2APOLBUSP2TDP1
SCHEMBL11484431 0.81 KMT2A (1.00) MEN1KMT2APOLBUSP2CASP1
SCHEMBL30870383 0.81 MEN1 (0.66) MEN1KMT2APOLBUSP2TDP1
SCHEMBL3502868 0.81 MEN1 (0.66) MEN1KMT2APOLBUSP2TDP1
SCHEMBL12566469 0.80 MEN1 (0.64) MEN1KMT2APOLBUSP2TDP1
SCHEMBL17629705 0.79 MEN1 (0.53) MEN1KMT2APOLBUSP2TDP1
SCHEMBL14255767 0.78 MAPT (0.63) MEN1KMT2APOLBUSP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9879300-B2 Method and array for identifying histone-code-related analytes UVic Industry Partnerships (CA) 2018-01-30 — — US claimed
US-20140357503-A1 METHOD AND ARRAY FOR IDENTIFYING HISTONE-CODE-RELATED ANALYTES UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2014-12-04 — — US claimed
WO-2013091074-A1 METHOD AND ARRAY FOR IDENTIFYING HISTONE-CODE-RELATED ANALYTES UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2013-06-27 — — WO claimed
CN-120607484-A N-phenylpiperazine fluorescent probe molecule and preparation method and application thereof 新乡医学院 2025-09-09 — — CN disclosed
US-11884956-B2 Methods for detecting mycobacteria with solvatochromic dye conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-01-30 — — US disclosed
US-11685835-B2 Ultra bright dimeric or polymeric dyes SONY CORPORATION (JP) 2023-06-27 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
EP-4137818-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS Sony Group Corporation (JP) 2023-02-22 — — EP disclosed
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE Sony Group Corporation (JP) 2022-07-14 — — US disclosed
US-20210285953-A1 POLYMERIC DYES HAVING A BACKBONE COMPRISING ORGANOPHOSPHATE UNITS Sony Group Corporation (JP) 2021-09-16 — — US disclosed
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2021-04-01 — — US disclosed
WO-2017105927-A1 POLYMERIC DYE RATIOMETRIC SENSOR FOR ANALYTE DETECTION AND METHODS OF USING THE SAME BECTON, DICKINSON AND COMPANY (US) 2017-06-22 — — WO disclosed
WO-2016138461-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS SONY CORPORATION (JP) 2016-09-01 — — WO disclosed
WO-2016046034-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2016-03-31 — — WO disclosed
US-20150268246-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2015-09-24 — — US disclosed
US-9034655-B2 Highly water-soluble, cationic luminescent labels SETA BIOMEDICALS, LLC (US) 2015-05-19 — — US disclosed
US-20140357503-A1 METHOD AND ARRAY FOR IDENTIFYING HISTONE-CODE-RELATED ANALYTES UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2014-12-04 — — US disclosed
WO-2013091074-A1 METHOD AND ARRAY FOR IDENTIFYING HISTONE-CODE-RELATED ANALYTES UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2013-06-27 — — WO disclosed
US-8440835-B2 Environmentally sensitive fluorophores MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-05-14 — — US disclosed
US-20100168428-A1 ENVIRONMENTALLY SENSITIVE FLUOROPHORES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168428-A1 ENVIRONMENTALLY SENSITIVE FLUOROPHORES PTMS, IK, PHAX MEN1 3976/4885KMT2A 4753/4885POLB 4198/4885
US-20220220314-A1 POLYMERIC DYES WITH LINKER GROUPS COMPRISING DEOXYRIBOSE H1-0, POLM, H1-2 MEN1 787/4885KMT2A 1614/4885POLB 10/4885
US-20210096135-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MEN1 1209/4885KMT2A 2550/4885POLB 3224/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 MEN1 1209/4885KMT2A 2550/4885POLB 3224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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