Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502848 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL380176 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3503244 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL10800123 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3503242 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL29540422 | 0.93 | CAMK2A (0.38) | TSHRLMNANFKB1PMP22GPR84 | |
| Stearic Acid SCHEMBL1531462 | 0.92 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL15642708 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL8680832 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL5738656 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210745-A1 | Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes | REACTIVE SURFACES, LTD. (US) | 2010-08-19 | — | — | US | disclosed |