Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502848 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3503244 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3501718 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL10800123 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3503242 | 1.00 | TSHR (0.43) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL29540422 | 0.93 | CAMK2A (0.38) | TSHRLMNANFKB1PMP22GPR84 | |
| Stearic Acid SCHEMBL1531462 | 0.92 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL15642708 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL8680832 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG | |
| SCHEMBL5738656 | 0.89 | FFAR4 (0.54) | TSHRGPR84FFAR1FFAR4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382177-B1 | PREPARATION OF ESTERS AND POLYOLS BY INITIAL OXIDATIVE CLEAVAGE OF FATTY ACIDS FOLLOWED BY ESTERIFICATION REACTIONS | BATTELLE MEMORIAL INSTITUTE (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2382294-B1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2019-02-13 | — | — | EP | disclosed |
| EP-2382293-B1 | SOLVENT-LESS PREPARATION OF POLYOLS BY OZONOLYSIS | BATTELLE MEMORIAL INSTITUTE (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2382292-B1 | PRE-ESTERIFICATION OF PRIMARY POLYOLS TO IMPROVE SOLUBILITY IN SOLVENTS USED IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2308955-B1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-22 | — | — | EP | disclosed |
| US-8877952-B2 | Pre-esterification of primary polyols to improve solubility in solvents used in the polyol process | BATTELLE MEMORIAL INSTITUTE (US) | 2014-11-04 | — | — | US | disclosed |
| US-8871960-B2 | Preparation of esters and polyols by initial oxidative cleavage of fatty acids followed by esterification reactions | BATTELLE MEMORIAL INSTITUTE (US) | 2014-10-28 | — | — | US | disclosed |
| US-8859794-B2 | Use of fatty acids as feed material in polyol process | BATTELLE MEMORIAL INSTITUTE (US) | 2014-10-14 | — | — | US | disclosed |
| US-8624047-B2 | Solvent-less preparation of polyols by ozonolysis | BATTELLE MEMORIAL INSTITUTE (US) | 2014-01-07 | — | — | US | disclosed |
| US-8178703-B2 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2012-05-15 | — | — | US | disclosed |
| WO-2010078505-A1 | PREPARATION OF ESTERS AND POLYOLS BY INITIAL OXIDATIVE CLEAVAGE OF FATTY ACIDS FOLLOWED BY ESTERIFICATION REACTIONS | BATTELLE MEMORIAL INSTITUTE (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010078491-A1 | PRE-ESTERIFICATION OF PRIMARY POLYOLS TO IMPROVE SOLUBILITY IN SOLVENTS USED IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010078498-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010078493-A1 | SOLVENT-LESS PREPARATION OF POLYOLS BY OZONOLYSIS | BATTELLE MEMORIAL INSTITUTE (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20090216040-A1 | Methods For Production Of Polyols From Oils And Their Use In the Production of Polyesters and Polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2009-08-27 | — | — | US | disclosed |
| EP-1883690-A2 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007027223-A2 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2007-03-08 | — | — | WO | disclosed |
| EP-0079629-B1 | THERMOSETTING RESINOUS BINDER COMPOSITIONS, THEIR PREPARATION AND THEIR USE AS COATING MATERIALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-05-15 | — | — | EP | disclosed |
| US-4405662-A | CROSSLINKER HAVING GAMMA-HYDROXYL OR AMINO GROUP | SHELL OIL COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0079629-A1 | Thermosetting resinous binder compositions, their preparation and their use as coating materials | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216040-A1 | Methods For Production Of Polyols From Oils And Their Use In the Production of Polyesters and Polyurethanes | FASN, MGLL, PUF60 | TSHR 4494/4885LMNA 706/4885NFKB1 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.