⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25164938 | 0.79 | — | — | |
| SCHEMBL24477575 | 0.77 | — | — | |
| SCHEMBL25164806 | 0.77 | — | — | |
| SCHEMBL24477581 | 0.75 | — | — | |
| SCHEMBL25165265 | 0.75 | — | — | |
| SCHEMBL25164974 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL15800362 | 0.70 | — | — | |
| SCHEMBL8317664 | 0.70 | — | — | |
| SCHEMBL10233235 | 0.70 | — | — | |
| SCHEMBL19085875 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095211-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-04-19 | — | — | US | disclosed |