⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11941601 | 1.00 | — | — | |
| SCHEMBL11941599 | 1.00 | — | — | |
| SCHEMBL10397241 | 1.00 | — | — | |
| SCHEMBL10397341 | 1.00 | — | — | |
| SCHEMBL3137288 | 0.81 | — | — | |
| SCHEMBL93553 | 0.78 | — | — | |
| SCHEMBL5868527 | 0.77 | — | — | |
| SCHEMBL18649757 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL3678923 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL9763067 | 0.75 | SPHK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461634-A | Preparation method of enzalutamide | JIANGSU HANSOH PHARMACEUTICAL GROUP LIANYUNGANG HONGCHUANG PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| EP-3250585-B1 | CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM S. AUREUS | YEDA RES & DEV (IL) | 2019-08-14 | — | — | EP | disclosed |
| CN-105461634-A | Preparation method of enzalutamide | JIANGSU HANSOH PHARMACEUTICAL GROUP LIANYUNGANG HONGCHUANG PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | disclosed |
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
| US-20100210745-A1 | Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes | REACTIVE SURFACES, LTD. (US) | 2010-08-19 | — | — | US | disclosed |