Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796996 | 0.91 | SPHK1 (0.55) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL7126662 | 0.81 | SPHK1 (0.41) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL27881588 | 0.79 | SPHK1 (0.40) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL1783784 | 0.77 | TSHR (0.46) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL11179784 | 0.77 | TSHR (0.46) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL13006892 | 0.77 | SPHK1 (0.39) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL1285427 | 0.76 | TSHR (0.36) | CYP3A4TSHRALDH1A1SMN1; SMN2FDPS | |
| SCHEMBL19895959 | 0.76 | — | — | |
| SCHEMBL19895957 | 0.76 | — | — | |
| SCHEMBL10397241 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004843-A | Reacting A Vinyl Epoxide With An Organolithium Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-02 | — | — | US | disclosed |
| EP-0029603-B1 | PROCESS FOR PREPARING PREDOMINANTLY Z-SUBSTITUTED ALLYLIC ALCOHOLS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-06-13 | — | — | EP | disclosed |
| EP-0029603-A1 | Process for preparing predominantly Z-substituted allylic alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-06-03 | — | — | EP | disclosed |