Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | POLB | P06746 | 5/20 | 0.66 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3504382 | 0.95 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3503153 | 0.89 | MEN1 (0.61) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3503519 | 0.87 | MEN1 (0.66) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL24270353 | 0.84 | MEN1 (0.59) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL26053794 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL16213594 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL31094030 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3503912 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL12660543 | 0.82 | MEN1 (0.63) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL29580722 | 0.82 | MEN1 (0.59) | MEN1KMT2APOLBUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2008106104-A2 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | PTMS, IK, PHAX | MEN1 3976/4885KMT2A 4753/4885POLB 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.