Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | POLB | P06746 | 5/20 | 0.69 |
| ▸ | USP2 | O75604 | 4/20 | 0.59 |
| ▸ | HEXA | P06865 | 4/20 | 0.57 |
| ▸ | HEXB | P07686 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094030 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL29581442 | 0.89 | MEN1 (0.61) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL29580722 | 0.86 | MEN1 (0.59) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL3504382 | 0.86 | MEN1 (0.69) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL3503912 | 0.86 | MEN1 (0.69) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL16213594 | 0.86 | MEN1 (0.69) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL29581473 | 0.85 | MEN1 (0.57) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL23373805 | 0.85 | MEN1 (0.64) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL29580895 | 0.84 | MEN1 (0.56) | MEN1KMT2APOLBUSP2HEXA | |
| SCHEMBL3502546 | 0.84 | MEN1 (0.66) | MEN1KMT2APOLBUSP2HEXA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2023-10-19 | — | — | US | disclosed |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2023-08-31 | — | — | US | disclosed |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | PSEN1, PSEN2, MAPT | MEN1 521/4885KMT2A 4003/4885POLB 3426/4885 |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | KIT, MACF1, IK | MEN1 1772/4885KMT2A 3253/4885POLB 2955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.