Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503314 | 1.00 | GRM2 (0.37) | GRM2GRM5F10CALML3MAOB | |
| SCHEMBL3503318 | 1.00 | GRM2 (0.37) | GRM2GRM5F10CALML3MAOB | |
| SCHEMBL3504084 | 1.00 | GRM2 (0.37) | GRM2GRM5F10CALML3MAOB | |
| SCHEMBL3503313 | 1.00 | GRM2 (0.37) | GRM2GRM5F10CALML3MAOB | |
| SCHEMBL3508402 | 0.97 | GRM2 (0.38) | GRM2GRM5F10CALML3MAOB | |
| SCHEMBL9186218 | 0.90 | GRM2 (0.37) | GRM2GRM5MAOBMAOA | |
| SCHEMBL8305866 | 0.89 | MAOB (0.38) | GRM2GRM5CALML3MAOBMAOA | |
| SCHEMBL9185352 | 0.87 | F10 (0.36) | GRM2GRM5F10MAOBMAOA | |
| SCHEMBL8305251 | 0.86 | MAOA (0.36) | GRM2GRM5F10MAOBMAOA | |
| SCHEMBL8305257 | 0.86 | MAOA (0.36) | GRM2GRM5F10MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | claimed |
| US-20100247543-A1 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
| US-20020168403-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-11-14 | — | — | US | disclosed |
| US-20020019421-A1 | Compositions and therapy for substance addiction | BIBERMAN RONI (IL) | 2002-02-14 | — | — | US | disclosed |
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |