⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6192366 | 0.78 | MAP4K4 (0.33) | — | |
| SCHEMBL3219040 | 0.77 | — | — | |
| SCHEMBL158301 | 0.77 | HTR2C (0.42) | — | |
| SCHEMBL350024 | 0.74 | — | — | |
| SCHEMBL6276304 | 0.74 | — | — | |
| SCHEMBL407722 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL11089923 | 0.73 | — | — | |
| SCHEMBL9657767 | 0.73 | — | — | |
| SCHEMBL350245 | 0.73 | — | — | |
| SCHEMBL407622 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| EP-4204400-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | Fibrogen, Inc. (US) | 2023-07-05 | — | — | EP | claimed |
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| EP-3625222-B1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-21 | — | — | EP | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| US-20200179383-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2020-06-11 | — | — | US | claimed |
| US-6617282-B2 | Useful as herbicides, defoliants and desiccants. | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-09 | — | — | US | claimed |
| US-6613718-B2 | 2,3-Dihydro-2-thioxo-pyrimidinone derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-02 | — | — | US | claimed |
| US-20030130122-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2003-07-10 | — | — | US | claimed |
| US-20030096990-A1 | Processes for preparing 3-phenyl-2,4(1H, 3H)-pyrimidinediones | ISHIHARA SANGYO KAISHA, LTD. | 2003-05-22 | — | — | US | claimed |
| WO-2003029225-A1 | ARYL ETHER DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-04-10 | — | — | WO | claimed |
| US-20020161224-A1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | PULMAN DAVID A (US) | 2002-10-31 | — | — | US | claimed |
| US-6333296-B1 | FOR CONTRILLING WEEDS | ISK AMERICAS INCORPORATED | 2001-12-25 | — | — | US | claimed |
| EP-0973395-A4 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0973395-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK Americas Incorporated (US) | 2000-01-26 | — | — | EP | claimed |
| WO-1998041093-A1 | DIARYL ETHERS AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INCORPORATED (US) | 1998-09-24 | — | — | WO | claimed |