⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6276304 | 0.76 | — | — | |
| SCHEMBL407722 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL3225026 | 0.76 | — | — | |
| SCHEMBL407622 | 0.74 | — | — | |
| SCHEMBL350470 | 0.74 | — | — | |
| SCHEMBL9657767 | 0.74 | — | — | |
| SCHEMBL11089923 | 0.74 | — | — | |
| SCHEMBL350245 | 0.74 | — | — | |
| SCHEMBL12505117 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL15819790 | 0.70 | KIF11 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | claimed |
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| EP-3625222-B1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-21 | — | — | EP | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| US-20200179383-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2020-06-11 | — | — | US | claimed |
| EP-3625222-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | claimed |
| CN-109952289-A | TRPV4 antagonist | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-106459076-B | Compound and composition for inducing cartilage to occur | 诺华股份有限公司 | 2019-01-04 | — | — | CN | claimed |
| EP-0201194-B1 | DIABROTICA LARVICIDAL AGENTS | ELI LILLY AND COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| US-4727075-A | Fungicidal 5-substituted pyrimidine derivatives, compositions, and method of use therefor | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | claimed |
| EP-0215307-A2 | Pyrimidin derivatives, process for their preparation and their use as microbicides | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | claimed |
| EP-0201194-A2 | Diabrotica larvicidal agents | ELI LILLY AND COMPANY (US) | 1986-11-12 | — | — | EP | claimed |
| EP-0201203-A2 | Method of treatment of plants with aniline derivatives | MAY & BAKER LIMITED (GB) | 1986-11-12 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4085099-A | AZO DYES | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1978-04-18 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |