Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 1.00 |
| ▸ | AOC2 | O75106 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | DAO | P14920 | 2/20 | 1.00 |
| ▸ | AOC3 | Q16853 | 15/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3506282 | 1.00 | MAOB (1.00) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL10615836 | 1.00 | MAOB (1.00) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL23718739 | 0.90 | AOC2 (0.81) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL23718741 | 0.90 | AOC2 (0.81) | MAOBAOC2MAOADAOAOC3 | |
| Hydrochloric Acid SCHEMBL23701794 | 0.89 | AOC2 (0.79) | MAOBAOC2MAOADAOAOC3 | |
| Hydrochloric Acid SCHEMBL23701736 | 0.89 | AOC2 (0.79) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL1294789 | 0.84 | MAOB (1.00) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL1294793 | 0.84 | MAOB (1.00) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL1294791 | 0.84 | MAOB (1.00) | MAOBAOC2MAOADAOAOC3 | |
| SCHEMBL1294159 | 0.82 | MAOB (0.73) | MAOBAOC2MAOADAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168013-B1 | FLUOROALLYLAMINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-02 | — | — | EP | claimed |
| EP-0168013-A1 | Fluoroallylamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-01-15 | — | — | EP | claimed |
| US-20100247543-A1 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS, S.A. (ES) | 2010-09-30 | — | — | US | disclosed |
| EP-2195029-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | Oryzon Genomics SA (ES) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009027349-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS SA (ES) | 2009-03-05 | — | — | WO | disclosed |
| CN-1008817-B | Process for preparing fluoroallylamine derivatives | MERRELL DOW PHARMACEVTICALS IN (US) | 1990-07-18 | — | — | CN | disclosed |
| EP-0168013-B1 | FLUOROALLYLAMINE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4699928-A | ANTIDEPRESSANTS, TREATMENT OF PARKINSON'S DISEASE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-10-13 | — | — | US | disclosed |
| CN-85106281-A | The preparation method of fluoroallylamine derivatives | — | 1987-02-18 | — | — | CN | disclosed |
| EP-0168013-A1 | Fluoroallylamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-01-15 | — | — | EP | disclosed |