Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | PGR | P06401 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.65 |
| ▸ | BLM | P54132 | 4/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507483 | 1.00 | SHBG (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10959929 | 0.99 | SHBG (0.65) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10959915 | 0.99 | SHBG (0.65) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10961047 | 0.90 | SHBG (0.64) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Potassium Ion SCHEMBL10959922 | 0.90 | TDP1 (0.67) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10961041 | 0.90 | SHBG (0.64) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL7497323 | 0.89 | SHBG (0.69) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL7497316 | 0.89 | SHBG (0.69) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9848864 | 0.89 | SHBG (0.69) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Topterone SCHEMBL8846971 | 0.88 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981327-B1 | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF TESTOSTERONE AND TESTOSTERONE PRECURSORS | GALEN CHEMICALS LTD (IE) | 2002-11-06 | — | — | EP | claimed |
| US-6416780-B1 | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors | GALEN (CHEMICALS) LIMITED (IE) | 2002-07-09 | — | — | US | claimed |
| EP-0981327-A2 | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF TESTOSTERONE AND TESTOSTERONE PRECURSORS | GALEN (CHEMICALS) LIMITED (IE) | 2000-03-01 | — | — | EP | claimed |
| WO-1998050016-A2 | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF TESTOSTERONE AND TESTOSTERONE PRECURSORS | GALEN (CHEMICALS) LIMITED (IE) | 1998-11-12 | — | — | WO | claimed |
| US-4267106-A | New process for the preparation 17β-hydroxy-3-oxo-17α-pregnene and pregnadiene-21-carboxylic acid γ-lactones | GIST BROCADES N.V. (NL) | 1981-05-12 | — | — | US | claimed |
| US-4057542-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | claimed |
| US-4057543-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | claimed |
| US-11918770-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-03-05 | — | — | US | disclosed |
| US-20220184362-A1 | Implants for Localized Drug Delivery and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-16 | — | — | US | disclosed |
| US-11324935-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-10 | — | — | US | disclosed |
| US-10912933-B2 | Implants for localized drug delivery and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-09 | — | — | US | disclosed |
| CN-111214701-A | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-06-02 | — | — | CN | disclosed |
| CN-106573133-B | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-03-03 | — | — | CN | disclosed |
| US-4150127-A | Novel steroid compounds having an oxygen function in the 19-position | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4057542-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4057543-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4057542-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4057543-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4057542-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4057543-A | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone | G. D. SEARLE & CO. (US) | 1977-11-08 | — | — | US | disclosed |