⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089722 | 0.73 | — | — | |
| SCHEMBL14047454 | 0.73 | — | — | |
| SCHEMBL5090365 | 0.67 | — | — | |
| SCHEMBL1579955 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL255878 | 0.64 | — | — | |
| SCHEMBL33887 | 0.62 | TDP1 (0.35) | — | |
| SCHEMBL1017270 | 0.61 | — | — | |
| SCHEMBL4816778 | 0.61 | TDP1 (0.40) | — | |
| SCHEMBL3679158 | 0.61 | — | — | |
| SCHEMBL28813862 | 0.61 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11065341-B2 | DE-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2021-07-20 | — | — | US | disclosed |
| US-20180154016-A1 | DE-N-Acetyl Sialic Acid Antigens, Antibodies Thereto, and Methods of Use in Cancer Therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | 2018-06-07 | — | — | US | disclosed |
| US-9872921-B2 | DE-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2018-01-23 | — | — | US | disclosed |
| EP-1976554-B1 | DE-N-ACETYL SIALIC ACID ANTIGENS, ANTIBODIES THERETO, AND METHODS OF USE IN CANCER THERAPY | CHILDRENS HOSP & RES CT OAK (US) | 2016-11-16 | — | — | EP | disclosed |
| US-20160184450-A1 | DE-N-Acetyl Sialic Acid Antigens, Antibodies Thereto, and Methods of Use in Cancer Therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER OAKLAND | 2016-06-30 | — | — | US | disclosed |
| US-9089513-B2 | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER OAKLAND (US) | 2015-07-28 | — | — | US | disclosed |
| US-20120219560-A1 | DE-N-Acetyl Sialic Acid Antigens, Antibodies Thereto, and Methods of Use in Cancer Therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-30 | — | — | US | disclosed |
| US-20100260762-A1 | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND | 2010-10-14 | — | — | US | disclosed |
| EP-1976554-A2 | DE-N-ACETYL SIALIC ACID ANTIGENS, ANTIBODIES THERETO, AND METHODS OF USE IN CANCER THERAPY | Children's Hospital & Research Center at Oakland (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007075921-A2 | DE-N-ACETYL SIALIC ACID ANTIGENS, ANTIBODIES THERETO, AND METHODS OF USE IN CANCER THERAPY | CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) | 2007-07-05 | — | — | WO | disclosed |