⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL9095544 | 0.74 | — | — | |
| Thiourea SCHEMBL5430249 | 0.67 | — | — | |
| SCHEMBL9412208 | 0.67 | — | — | |
| Thioacetamide SCHEMBL29019876 | 0.67 | — | — | |
| SCHEMBL6958171 | 0.67 | — | — | |
| SCHEMBL6632858 | 0.67 | — | — | |
| SCHEMBL6224420 | 0.67 | — | — | |
| SCHEMBL9131991 | 0.67 | — | — | |
| SCHEMBL10766138 | 0.67 | — | — | |
| Thiourea SCHEMBL850383 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1901762-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | Cancure Laboratories, LLC (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | claimed |
| WO-2007008376-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | CANCURE LABORATORIES, LLC (US) | 2007-01-18 | — | — | WO | claimed |
| US-20070010427-A1 | Use of one or more metal carriers to selectively kill mammalian cells | CANCURE LABORATORIES, LLC (US) | 2007-01-11 | — | — | US | claimed |
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| EP-0874846-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Novartis AG (CH) | 1998-11-04 | — | — | EP | claimed |
| WO-1997016452-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-05-09 | — | — | WO | claimed |
| US-20100298352-A1 | SMALL MOLECULE INHIBITORS OF CANCER STEM CELLS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2010-11-25 | — | — | US | disclosed |
| US-20100137557-A1 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | CANCURE LABORATORIES LLC (US) | 2010-06-03 | — | — | US | disclosed |
| US-7655620-B2 | Toxic metal-protein (cycsteines) complex targeted for cells/tissues to enrich the site with metal ligand; administering a dithiocarbonyl having greater affinity for the metal and permeability of the membrane to release the metal inside the cell; antitumor, -carcinogenic agents; apoptosisdeath | CANCURE LABORATORIES, LLC (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1901762-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | Cancure Laboratories, LLC (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007008376-A2 | USE OF ONE OR MORE METAL CARRIERS TO SELECTIVELY KILL MAMMALIAN CELLS | CANCURE LABORATORIES, LLC (US) | 2007-01-18 | — | — | WO | disclosed |
| EP-1153024-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | Novartis AG (CH) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000049018-A1 | 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |
| EP-0984923-A1 | O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054125-A1 | O-BENZYL OXIME ETHERS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1998-12-03 | — | — | WO | disclosed |
| EP-0874846-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Novartis AG (CH) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997016452-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-05-09 | — | — | WO | disclosed |
| US-4093802-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-06-06 | — | — | US | disclosed |