⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL8657126 | 0.86 | — | — | |
| Guanidine SCHEMBL29044101 | 0.82 | TSHR (0.31) | — | |
| Guanidine SCHEMBL1903839 | 0.82 | TSHR (0.31) | — | |
| Guanidine SCHEMBL56028 | 0.82 | — | — | |
| Thiourea SCHEMBL9095544 | 0.80 | — | — | |
| Guanidine SCHEMBL6851202 | 0.78 | — | — | |
| Thiourea SCHEMBL18528963 | 0.78 | TSHR (0.50) | — | |
| Guanidine SCHEMBL7755519 | 0.78 | — | — | |
| Guanidine SCHEMBL31206959 | 0.78 | — | — | |
| Thiourea SCHEMBL5421224 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732535-B | A kind of improved azilide compound and its preparation method and application | 中国农业大学 | 2019-03-19 | — | — | CN | claimed |
| WO-2024030954-A1 | CHEMICAL MODIFICATION OF ANTIBODIES AND FUNCTIONAL FRAGMENTS THEREOF | NAUTILUS SUBSIDIARY, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| WO-2023102336-A1 | PARTICLE-BASED ISOLATION OF PROTEINS AND OTHER ANALYTES | NAUTILUS SUBSIDIARY, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-101454004-A | Pyridone sulfonamides and pyridone sulfamides as mek inhibitors | ARDEA BIOSCIENCES INC (US) | 2009-06-10 | — | — | CN | disclosed |
| US-7214762-B1 | Redox-active polymer and electrode comprising the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-05-08 | — | — | US | disclosed |
| US-5166180-A | Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-24 | — | — | US | disclosed |
| EP-0324521-A2 | Method of treating haematologic diseases and pharmaceutical compositions to be used therefor | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-07-19 | — | — | EP | disclosed |