Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | EPOR | P19235 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508860 | 1.00 | LTB4R (0.46) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3507303 | 0.95 | LTB4R (0.46) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3507297 | 0.95 | LTB4R (0.46) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3508522 | 0.93 | PPARG (0.49) | PPARGPSEN1PTGESALOX5PPARD | |
| SCHEMBL3508526 | 0.93 | PPARG (0.49) | PPARGPSEN1PTGESALOX5PPARD | |
| SCHEMBL3506356 | 0.91 | PPARG (0.45) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3506351 | 0.91 | PPARG (0.45) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL14051593 | 0.91 | PPARG (0.45) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3508438 | 0.90 | PPARG (0.44) | LTB4RLTB4R2PPARGPSEN1PTGES | |
| SCHEMBL3508435 | 0.90 | PPARG (0.44) | LTB4RLTB4R2PPARGPSEN1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | LTB4R 634/4885LTB4R2 614/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.