Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.73 |
| ▸ | BCR | P11274 | 6/20 | 0.73 |
| ▸ | PRKCA | P17252 | 4/20 | 0.73 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 4/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | PRKACA | P17612 | 2/20 | 0.59 |
| ▸ | PRKACG | P22612 | 2/20 | 0.59 |
| ▸ | PRKACB | P22694 | 2/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509891 | 0.91 | ABL1 (0.74) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837776 | 0.90 | ABL1 (0.70) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837795 | 0.87 | ABL1 (0.80) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3511553 | 0.87 | CSNK2A1 (0.66) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3510088 | 0.86 | CSNK2A1 (0.70) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837915 | 0.86 | ABL1 (0.79) | ABL1BCRPRKCACSNK2A1SRC | |
| Hydrochloric Acid SCHEMBL3511724 | 0.86 | CSNK2A1 (0.65) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL8837787 | 0.85 | ABL1 (0.71) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3514107 | 0.85 | CSNK2A1 (0.66) | ABL1BCRPRKCACSNK2A1SRC | |
| SCHEMBL3511896 | 0.85 | CSNK2A1 (0.76) | ABL1BCRPRKCACSNK2A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | claimed |
| EP-2155713-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | Bayer CropScience SA (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008138992-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-11-20 | — | — | WO | claimed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| EP-2155713-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | Bayer CropScience SA (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008138992-A1 | FUNGICIDES PHENYL-PYRIMDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-11-20 | — | — | WO | disclosed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0672035-A1 | PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| WO-1995009847-A1 | PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CIBA-GEIGY AG (CH) | 1995-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137309-A1 | FUNGICIDES PHENYL-PYRIMIDNYL-AMINO DERIVATIVES | CYP1A1, CYP1A2, PAH | ABL1 268/4885BCR 2868/4885PRKCA 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.