Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Phenacemide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenacemide SCHEMBL23234284 | 0.98 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL699925 | 0.87 | MEN1 (0.71) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL3269788 | 0.84 | MEN1 (0.57) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL3565748 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| Phenacemide SCHEMBL28505156 | 0.83 | POLB (0.55) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL6470572 | 0.83 | MEN1 (0.65) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL27406480 | 0.82 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL3512351 | 0.80 | HDAC2 (0.63) | KMT2AHDAC8HDAC6ALDH1A1LMNA | |
| SCHEMBL27840844 | 0.80 | GAA (0.59) | KMT2AALDH1A1LMNAMAPK8GAA | |
| SCHEMBL17866854 | 0.80 | MEN1 (0.52) | MEN1KMT2AHDAC8HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7488 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| US-12594256-B2 | A19-144, A2-73 and certain anticholinesterase inhibitor compositions and method for anti-seizure therapy | ANAVEX LIFE SCIENCES CORP. (US) | 2026-04-07 | — | — | US | claimed |
| EP-3518975-B1 | FORMULATION COMPRISING FENFLURAMINE AND CANNABIDIOL AND ITS USE IN THE TREATMENT OF SEIZURES | ZOGENIX INTERNATIONAL LTD (GB) | 2025-04-09 | — | — | EP | claimed |
| EP-4396249-A1 | TWO-COMPONENT STRUCTURAL ADHESIVE | DDP Specialty Electronic Materials US, LLC (US) | 2024-07-10 | — | — | EP | claimed |
| CN-116959653-A | Method for establishing diagnosis time-effect-based COVID-19 triage system, system and triage method | 广州医科大学附属第一医院 | 2023-10-27 | — | — | CN | claimed |
| US-11786487-B2 | Formulation for inhibiting formation of 5-HT2B agonists and methods of using same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-10-17 | — | — | US | claimed |
| US-20230301961-A1 | A19-144, A2-73 and Certain Anticholinesterase Inhibitor Compositions and Method for Anti-Seizure Therapy | ANAVEX LIFE SCIENCES CORP. (US) | 2023-09-28 | — | — | US | claimed |
| WO-2023178250-A1 | TREATMENT OF TUBEROUS SCLEROSIS WITH MIRDAMETINIB | SpringWorks Therapeutics Inc. (US) | 2023-09-21 | — | — | WO | claimed |
| US-11759440-B2 | Formulation for inhibiting formation of 5-HT2B agonists and methods of using same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-09-19 | — | — | US | claimed |
| US-20230279276-A1 | BONDING DISSIMILAR MATERIALS USING RADIO FREQUENCY WAVE CURING | DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) | 2023-09-07 | — | — | US | claimed |
| EP-0564253-B1 | Process for preparing alkoxy-terminated organosiloxane fluids using organo-lithium reagents | LOCTITE CORP (US) | 1998-12-09 | — | — | EP | claimed |
| WO-1998018610-A1 | EMBEDDING AND ENCAPSULATION OF CONTROLLED RELEASE PARTICLES | LENGERICH BERNHARD H VAN (US) | 1998-05-07 | — | — | WO | claimed |
| WO-1998007447-A1 | ANTICONVULSANT CONTAINING COMPOSITION FOR TREATING NEUROPATHIC PAIN | ALGOS PHARMACEUTICAL CORPORATION (US) | 1998-02-26 | — | — | WO | claimed |
| EP-0758228-A1 | EFFECTIVE DOSAGE FORM FOR ANTIEPILEPTIC DRUGS | ALZA CORPORATION (US) | 1997-02-19 | — | — | EP | claimed |
| WO-1995029665-A1 | EFFECTIVE DOSAGE FORM FOR ANTIEPILEPTIC DRUGS | ALZA CORPORATION (US) | 1995-11-09 | — | — | WO | claimed |
| WO-1995008513-A1 | BIOCOMPOSITE COMPRISING A MICROORGANISM AND AN ADDITIVE IN A FORMULATION MATRIX FOR BIOREMEDIATION AND POLLUTION CONTROL | SBP TECHNOLOGIES, INC. (US) | 1995-03-30 | — | — | WO | claimed |
| US-5192550-A | Dosage form for treating central nervous system disorders | ALZA CORPORATION (US) | 1993-03-09 | — | — | US | claimed |
| EP-0093465-B1 | PREPARATION OF 6-ALPHA-BROMO- AND/OR 6,6-DIBROMO-PENICILLANIC ACID 1,1-DIOXIDES | GIST-BROCADES N.V. (NL) | 1987-05-06 | — | — | EP | claimed |
| US-4619786-A | DIAZOTIZING, NITROSATING, THEN BROMINATING | GIST-BROCADES N.V. (NL) | 1986-10-28 | — | — | US | claimed |
| EP-0093465-A2 | Preparation of 6-alpha-bromo- and/or 6,6-dibromo-penicillanic acid 1,1-dioxides | GIST-BROCADES N.V. (NL) | 1983-11-09 | — | — | EP | claimed |