Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.60 |
| ▸ | FAP | Q12884 | 5/20 | 0.60 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511981 | 1.00 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6162266 | 0.80 | DPP4 (0.73) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24989201 | 0.79 | DPP4 (0.69) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14985801 | 0.78 | DPP4 (0.67) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7843703 | 0.77 | DPP4 (0.56) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6436643 | 0.77 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7375090 | 0.77 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL31026624 | 0.77 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5900809 | 0.77 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3726263 | 0.77 | ACE (0.70) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297751-A1 | Non-Ribosomal Peptide Synthetases | WONDRUG BIOSCIENCES GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| US-20100285563-A1 | Non-Ribosomal Peptide Synthetases | WONDRUG BIOSCIENCES GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| EP-1255816-B1 | TAILORED PEPTIDE SYNTHETASES, A METHOD FOR THEIR PRODUCTION AND THE USE THEREOF | CUBIST PHARMACEUTICAL INC (US) | 2006-06-21 | — | — | EP | disclosed |