Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.52 |
| ▸ | PPARA | Q07869 | 19/20 | 0.52 |
| ▸ | PPARG | P37231 | 14/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512407 | 1.00 | PPARD (0.52) | PPARDPPARAPPARG | |
| SCHEMBL3510967 | 0.90 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL3510970 | 0.90 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL1935430 | 0.88 | PPARA (0.55) | PPARDPPARAPPARG | |
| SCHEMBL2031382 | 0.84 | PPARA (0.56) | PPARDPPARAPPARG | |
| SCHEMBL2031380 | 0.84 | PPARA (0.56) | PPARDPPARAPPARG | |
| SCHEMBL3512485 | 0.78 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL1934851 | 0.78 | NPC1 (0.44) | PPARDPPARAPPARG | |
| SCHEMBL1934897 | 0.78 | NPC1 (0.56) | PPARDPPARAPPARG | |
| SCHEMBL3511782 | 0.77 | PPARD (0.54) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188148-B2 | Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof | GENFIT (FR) | 2012-05-29 | — | — | US | claimed |
| US-8188148-B2 | Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof | GENFIT (FR) | 2012-05-29 | — | — | US | disclosed |
| US-20100286276-A1 | Substituted 1,3-Diphenylpropane Derivatives, Preparations and Uses Thereof | GENFIT (FR) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286276-A1 | Substituted 1,3-Diphenylpropane Derivatives, Preparations and Uses Thereof | DPP3, DPP8, DPP4 | PPARD 9/4885PPARA 11/4885PPARG 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.