Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567721 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1SLC22A6KISS1RMAPT | |
| SCHEMBL17066345 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1SLC22A6KISS1RMAPT | |
| SCHEMBL14430862 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1SLC22A6KISS1RMAPT | |
| SCHEMBL10661813 | 0.97 | ALDH1A1 (0.48) | ALDH1A1TDP1SLC22A6KISS1RMAPT | |
| SCHEMBL20530439 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1SLC22A6KISS1R | |
| SCHEMBL2470752 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1SLC22A6KISS1R | |
| SCHEMBL14503023 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1SLC22A6KISS1RTRPA1 | |
| SCHEMBL10622508 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1SLC22A6KISS1R | |
| SCHEMBL2337444 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1SLC22A6MAPTTRPA1 | |
| SCHEMBL5317803 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRTP53TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296995-B2 | Vaccines against Bordetella pertussis based on LPS glycosyltransferase mutants | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2016-03-29 | — | — | US | disclosed |
| US-20100291153-A1 | VACCINES AGAINST BORDETELLA PERTUSSIS BASED ON LPS GLYCOSYLTRANSFERASE MUTANTS | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2010-11-18 | — | — | US | disclosed |