Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3511485 | 1.00 | S1PR1 (0.36) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL13165878 | 0.97 | S1PR1 (0.34) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL13165896 | 0.95 | S1PR1 (0.36) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL3508301 | 0.91 | S1PR1 (0.35) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3508839 | 0.91 | S1PR1 (0.35) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13165879 | 0.88 | S1PR1 (0.33) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3512678 | 0.87 | NAMPT (0.40) | — | |
| SCHEMBL3511760 | 0.87 | NAMPT (0.40) | — | |
| SCHEMBL12345100 | 0.85 | S1PR1 (0.46) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL13165876 | 0.85 | LTB4R (0.42) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045325-B1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO CO LTD (JP) | 2012-09-19 | — | — | EP | disclosed |
| EP-2045325-B1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO CO LTD (JP) | 2012-09-19 | — | — | EP | disclosed |
| US-20100248227-A1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100248227-A1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100248227-A1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2045325-A1 | DRUG-PHOSPHORYLATING ENZYME | Daiichi Sankyo Company, Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| EP-2045325-A1 | DRUG-PHOSPHORYLATING ENZYME | Daiichi Sankyo Company, Limited (JP) | 2009-04-08 | — | — | EP | disclosed |