Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Oxcarbazepine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A known ✓ | P35499 | 1/20 | 0.46 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | PABPC1 | P11940 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxcarbazepine SCHEMBL29359799 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL4655725 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL29433241 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL27944289 | 0.98 | KDM4E (0.97) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL17372732 | 0.98 | KDM4E (0.97) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL5652834 | 0.94 | KDM4E (0.89) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL29123953 | 0.94 | ALDH1A1 (0.89) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL2885435 | 0.94 | KDM4E (0.89) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL321371 | 0.92 | KDM4E (0.84) | KDM4EALDH1A1CYP3A4MAPTMEN1 | |
| Oxcarbazepine SCHEMBL2328082 | 0.92 | KDM4E (0.84) | KDM4EALDH1A1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 18489 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| US-20260137654-A1 | COMPOUNDS AND METHODS FOR TREATING AN EPILEPTIC DISORDER | THE REGENTS OF THE UNIV OF CALIFORNIA (US) | 2026-05-21 | — | — | US | claimed |
| CN-122038556-A | Method for predicting sodium valproate therapeutic response based on TPH2 gene polymorphism, kit and application thereof | 深圳市宝安区妇幼保健院 | 2026-05-15 | — | — | CN | claimed |
| CN-120622619-B | Method for treating dibenzo organic pollutants in water body | 广东省科学院生态环境与土壤研究所 | 2026-05-12 | — | — | CN | claimed |
| US-20260124211-A1 | COMPOSITION CONTAINING LAMOTRIGINE, AND PREPARATION METHOD AND USE THEREOF | SHANGHAI AUCTA PHARMACEUTICALS CO., LTD. (CN) | 2026-05-07 | — | — | US | claimed |
| EP-4736841-A1 | A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT | IQ medical GmbH (DE) | 2026-05-06 | — | — | EP | claimed |
| US-12595237-B2 | Lamotrigine hydrate crystal form, preparation method therefor, and composition containing same | SHANGHAI AUCTA PHARMACEUTICALS CO., LTD. (CN) | 2026-04-07 | — | — | US | claimed |
| US-12594256-B2 | A19-144, A2-73 and certain anticholinesterase inhibitor compositions and method for anti-seizure therapy | ANAVEX LIFE SCIENCES CORP. (US) | 2026-04-07 | — | — | US | claimed |
| US-20260092932-A1 | METHODS AND COMPOSITIONS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDER | THE JOHNSON CENTER FOR CHILD HEALTH AND DEV (US) | 2026-04-02 | — | — | US | claimed |
| EP-4288042-B1 | COMBINATION THERAPY FOR TREATING EXECUTIVE FUNCTION DISORDERS | ANAKA PHARMACEUTICALS INC (US) | 2026-04-01 | — | — | EP | claimed |
| WO-1995029665-A1 | EFFECTIVE DOSAGE FORM FOR ANTIEPILEPTIC DRUGS | ALZA CORPORATION (US) | 1995-11-09 | — | — | WO | claimed |
| EP-0646374-A1 | Double-coated oxcarbazepine containing tablets | CIBA-GEIGY AG (CH) | 1995-04-05 | — | — | EP | claimed |
| US-4559174-A | NITRATION, REDUCTION AND HYDROLYSIS OF 5-CYANO5H-DIBENZ/B,FLAZEPINE | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | claimed |
| EP-0028028-B1 | PROCESSES FOR THE PREPARATION OF AN OXO COMPOUND, AND INTERMEDIATES REQUIRED THEREFOR | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | claimed |
| EP-0050589-B1 | PHARMACEUTICAL COMPOSITIONS WITH AN ANTI-EPILEPTIC AND ANTI-NEURALGIC EFFECT, AND PROCESS FOR THEIR MANUFACTURE | CIBA-GEIGY AG (CH) | 1984-09-12 | — | — | EP | claimed |
| US-4452738-A | Process for the manufacture of 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,]azepine | CIBA-GEIGY CORPORATION (US) | 1984-06-05 | — | — | US | claimed |
| US-4431641-A | AN ANTICONVULSANT DIBENZ/B,F/AZEPINE POTENTIATED BY A VINCAMINE OR PIRACETAM DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | claimed |
| US-4409212-A | Method of preventing and treating cerebral insufficiency | CIBA-GEIGY CORPORATION (US) | 1983-10-11 | — | — | US | claimed |
| EP-0050589-A1 | Pharmaceutical compositions with an anti-epileptic and anti-neuralgic effect, and process for their manufacture | CIBA-GEIGY AG (CH) | 1982-04-28 | — | — | EP | claimed |
| EP-0028028-A2 | Processes for the preparation of an oxo compound, and intermediates required therefor | CIBA-GEIGY AG (CH) | 1981-05-06 | — | — | EP | claimed |