Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273004 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL10631088 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL148701 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL993588 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL10579468 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL9436902 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL352163 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL8436544 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL6758775 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 | |
| SCHEMBL22325587 | 1.00 | EPHX1 (0.48) | EPHX1FAAHSMN1; SMN2ACE2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197899-B1 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA- BETA3-AMINOACYL RESIDUE AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2014-09-03 | — | — | EP | claimed |
| US-8603968-B2 | Cyclic peptides comprising at least one aza-β3-aminoacyl residue and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | claimed |
| US-20100305027-A1 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA-B3-AMINOACYL RESIDUE AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-12-02 | — | — | US | claimed |
| EP-2197899-A2 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA- BETA3-AMINOACYL RESIDUE AND USES THEREOF | Centre National de la Recherche Scientifique (FR) | 2010-06-23 | — | — | EP | claimed |
| WO-2009083663-A2 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA-Β3-AMINOACYL RESIDUE AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-07-09 | — | — | WO | claimed |
| US-5977035-A | MIXTURE CONTAINING BORATE BUFFER | TOMEY TECHNOLOGY CORPORATION (JP) | 1999-11-02 | — | — | US | claimed |
| EP-0826379-A2 | Liquid agent for contact lens containing carboxylated amine as a preservative or sterilizing component | TOMEY TECHNOLOGY CORPORATION (JP) | 1998-03-04 | — | — | EP | claimed |
| EP-3638678-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | Modernatx, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| WO-2018232120-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2018-12-20 | — | — | WO | disclosed |
| EP-3394030-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | Modernatx, Inc. (US) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017112865-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS | MODERNATX, INC. (US) | 2017-06-29 | — | — | WO | disclosed |
| EP-2197899-B1 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA- BETA3-AMINOACYL RESIDUE AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2014-09-03 | — | — | EP | disclosed |
| US-8603968-B2 | Cyclic peptides comprising at least one aza-β3-aminoacyl residue and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-10 | — | — | US | disclosed |
| US-20100305027-A1 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA-B3-AMINOACYL RESIDUE AND THEIR USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-12-02 | — | — | US | disclosed |
| EP-2197899-A2 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA- BETA3-AMINOACYL RESIDUE AND USES THEREOF | Centre National de la Recherche Scientifique (FR) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009083663-A2 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA-Β3-AMINOACYL RESIDUE AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-07-09 | — | — | WO | disclosed |
| US-5977035-A | MIXTURE CONTAINING BORATE BUFFER | TOMEY TECHNOLOGY CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0826379-A2 | Liquid agent for contact lens containing carboxylated amine as a preservative or sterilizing component | TOMEY TECHNOLOGY CORPORATION (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-4378411-A | HAVING ETHLENICALLY UNSATURATED PEPTIDE GROUPS; FOR GRAPHIC ARTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-03-29 | — | — | US | disclosed |
| US-4304705-A | Radiation-curable polymers containing pendant unsaturated peptide groups derived from azlactone polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305027-A1 | CYCLIC PEPTIDES COMPRISING AT LEAST ONE AZA-B3-AMINOACYL RESIDUE AND THEIR USES | NPR3, VIP, ANPEP | EPHX1 4470/4885FAAH 4405/4885SMN1; SMN2 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.