Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514267 | 1.00 | CA2 (0.42) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL226707 | 0.86 | CA2 (0.50) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL183724 | 0.86 | CA2 (0.50) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL225441 | 0.86 | CA2 (0.50) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL5665387 | 0.81 | CA2 (0.38) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL5665383 | 0.81 | CA2 (0.38) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL11851900 | 0.80 | RECQL (0.50) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL5611375 | 0.79 | CA2 (0.49) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL5611373 | 0.79 | CA2 (0.49) | CA2ALDH1A1RECQLCYP3A4TSHR | |
| SCHEMBL5611571 | 0.78 | FNTA (0.49) | CA2ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |