Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.64 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 10/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514785 | 1.00 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL6232483 | 0.84 | SLC7A5 (0.62) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL14742206 | 0.82 | ENPEP (0.58) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL5286582 | 0.81 | SLC1A2 (0.67) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL18229135 | 0.80 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL2298501 | 0.80 | SLC1A2 (0.64) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL24520313 | 0.79 | SLC7A5 (0.52) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL427560 | 0.78 | — | — | |
| Hydrogen Peroxide SCHEMBL2783488 | 0.78 | — | — | |
| SCHEMBL2050880 | 0.78 | SLC1A2 (0.61) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765910-B2 | Method for amidating polypeptides with basic amino acid C-terminals by means of specific endoproteases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| US-20100311112-A1 | METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINO ACID C-TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | disclosed |