SCHEMBL3514844

SCHEMBL3514844

O=Cc1ccccc1OP(=O)(Oc1ccccc1C=O)Oc1ccccc1C=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 4/20 0.71
ALDH1A1 P00352 6/20 0.57
HPGD P15428 1/20 0.57
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
LMNA P02545 3/20 0.53
KMT2A Q03164 3/20 0.53
GAA P10253 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 1/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TSHR P16473 1/20 0.41
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18574335 0.88 SRC (0.62) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL31509836 0.84 SRC (0.57) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL6272822 0.84 SRC (0.57) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL3514846 0.83 SRC (1.00) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL31127741 0.81 SRC (0.48) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL29153361 0.80 SRC (0.62) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL11217115 0.79 SRC (0.61) SRCALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL7210055 0.78 SRC (0.46) SRCHTTSMN1; SMN2LMNAKMT2A
SCHEMBL7210051 0.78 SRC (0.46) SRCHTTSMN1; SMN2LMNAKMT2A
SCHEMBL4434944 0.77 LMNA (0.75) SRCALDH1A1HPGDHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100285601-A1 METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-11 US disclosed
US-20100194409-A1 METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-08-05 US disclosed
WO-2009041917-A1 METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-04-02 WO disclosed
WO-2008020813-A1 METHOD OF ELECTRICALLY DETECTING A BIOLOGICAL ANALYTE MOLECULE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-02-21 WO disclosed