Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diacetylmorphine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 13/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.70 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diacetylmorphine SCHEMBL25681429 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16922136 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL29631710 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL17302926 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL14463869 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16183153 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16922130 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL13998950 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL10381363 | 1.00 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL6455951 | 0.99 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 47607 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747639-A2 | BETA-GALACTOSIDASE ENZYME-BASED IMMUNOASSAY | Abbott Diagnostics Scarborough, Inc. (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| US-12594388-B2 | Device to deliver a predetermined amount of a substance to a natural orifice of the body | APTARGROUP, INC. (US) | 2026-04-07 | — | — | US | claimed |
| EP-4714444-A1 | PREPARATION FOR AND USE OF CANNABIDIOL DERIVATIVE DRUGS | Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) | 2026-03-25 | — | — | EP | claimed |
| US-12584892-B2 | Apparatus and methods for detecting and quantifying analytes | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2026-03-24 | — | — | US | claimed |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2026-03-12 | — | — | US | claimed |
| US-12569478-B2 | Sequestration compounds for treatment of substance use disorder and uses thereof | CLEAR SCIENTIFIC, INC. (US) | 2026-03-10 | — | — | US | claimed |
| EP-4698287-A1 | ANTIMICROBIAL AND DRUG-NEUTRALIZING COMPOSITION | SoRite, LLC (US) | 2026-02-25 | — | — | EP | claimed |
| US-12544389-B2 | Stable cannabinoid formulations | FRESH CUT DEVELOPMENT, LLC (CA) | 2026-02-10 | — | — | US | claimed |
| EP-0062277-A1 | A method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays | Baker Instruments Corporation (US) | 1982-10-13 | — | — | EP | claimed |
| US-4353886-A | DETECTION OF NARCOTIC VAPORS BY COMPLEXING WITH ANTIBODY | IRT CORPORATION (US) | 1982-10-12 | — | — | US | claimed |
| US-4223004-A | DETECTING UNAUTHORIZED SUPPLEMENTAL DOSAGES USING DRUG AND AN ISOTOPICALLY DISTINCT ANALOG | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 1980-09-16 | — | — | US | claimed |
| US-4126684-A | 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | claimed |
| US-4110078-A | CHLOROPLATINIC ACID, COBALTOUS THIOCYANATE, HYDROCARBON LIQUID | ZELONIS PAUL THOMAS | 1978-08-29 | — | — | US | claimed |
| US-4104029-A | CHEMILUMINESCENT LABELING | MAIER JR CHARLES L | 1978-08-01 | — | — | US | claimed |
| US-4064228-A | Antigens and immunoassays for morphine and related 3-oxybenzomorphan compounds | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4022878-A | NATIVE HOMOLOGOUS HAPTEN OR ANTIGEN | BIOLOGICAL DEVELOPMENTS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-3972992-A | Diagnostic test for opium alkaloids | HOFFMANN-LA ROCHE INC. (US) | 1976-08-03 | — | — | US | claimed |
| US-3955926-A | COLORIMETRIC ANALYSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-05-11 | — | — | US | claimed |