Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 4/20 | 0.63 |
| ▸ | INSR | P06213 | 2/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12989676 | 1.00 | HSPD1 (0.64) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3516014 | 1.00 | HSPD1 (0.64) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL12990166 | 0.86 | TTR (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3364823 | 0.86 | TTR (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3364826 | 0.86 | TTR (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3364737 | 0.86 | MEN1 (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL3364742 | 0.86 | MEN1 (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL12990163 | 0.86 | MEN1 (0.55) | HSPD1HSPE1IGF1RINSRPIK3CG | |
| SCHEMBL13002910 | 0.79 | MYC (0.46) | HSPD1HSPE1IGF1RINSRMYC | |
| SCHEMBL3392771 | 0.79 | HSPD1 (0.57) | HSPD1HSPE1IGF1RINSRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331315-A1 | RHODANINES AND RELATED HETEROCYCLES AS KINASE INHIBITORS | PIM2, PIM1, CDK2 | HSPD1 1307/4885HSPE1 1252/4885IGF1R 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.