SCHEMBL3516306

SCHEMBL3516306

N#Cc1ccc(Cc2ncc[nH]2)cc1Oc1cccc(CN2CCCCC2)c1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.51
FNTB P49356 20/20 0.51
PGGT1B P53609 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3518730 0.81 FNTA (0.56) FNTAFNTBPGGT1B
SCHEMBL3515254 0.81 FNTA (0.45) FNTAFNTBPGGT1B
SCHEMBL5553357 0.80 FNTA (0.42) FNTAFNTBPGGT1B
SCHEMBL3503158 0.79 FNTA (0.74) FNTAFNTBPGGT1B
SCHEMBL3516041 0.78 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL3518902 0.78 CYP19A1 (0.40) FNTAFNTBPGGT1B
SCHEMBL5548771 0.78 FNTA (0.56) FNTAFNTBPGGT1B
SCHEMBL5552124 0.77 FNTA (0.59) FNTAFNTBPGGT1B
SCHEMBL3515326 0.77 FNTA (0.39) FNTAFNTBPGGT1B
SCHEMBL3516881 0.77 FNTA (0.68) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155197-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES Link Medicine Corporation (US) 2010-02-24 EP disclosed
WO-2008112525-A2 TREATMENT OF LYSOSOMAL STORAGE DISEASES LINK MEDICINE CORPORATION (US) 2008-09-18 WO disclosed