Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 17/20 | 0.40 |
| ▸ | FNTB | P49356 | 17/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 16/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515326 | 0.99 | FNTA (0.39) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL5548771 | 0.83 | FNTA (0.56) | CYP19A1FNTAFNTBPGGT1BTAAR1 | |
| SCHEMBL8130724 | 0.82 | TAAR1 (0.38) | FNTAFNTBPGGT1BTAAR1 | |
| SCHEMBL3519840 | 0.82 | SCN9A (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL3515222 | 0.81 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL3518730 | 0.81 | FNTA (0.56) | CYP19A1FNTAFNTBPGGT1BTAAR1 | |
| SCHEMBL3515256 | 0.80 | FNTA (0.46) | CYP19A1FNTAFNTBPGGT1BTAAR1 | |
| SCHEMBL3515254 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL3516306 | 0.78 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL3516600 | 0.78 | FNTA (0.37) | FNTAFNTBPGGT1BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059930-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | claimed |
| EP-1021188-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1999017777-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | claimed |
| EP-2155197-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | Link Medicine Corporation (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008112525-A2 | TREATMENT OF LYSOSOMAL STORAGE DISEASES | LINK MEDICINE CORPORATION (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2000059930-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-1021188-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999017777-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | disclosed |