Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475186 | 0.90 | TDP1 (0.56) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL2475190 | 0.90 | TDP1 (0.56) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL2478667 | 0.90 | TDP1 (0.56) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL10498224 | 0.86 | HCAR2 (0.47) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL10498231 | 0.86 | HCAR2 (0.47) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL9135761 | 0.82 | HCAR2 (0.55) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL6453889 | 0.82 | ATM (0.55) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL3482913 | 0.82 | HCAR2 (0.62) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL3482909 | 0.82 | HCAR2 (0.62) | HCAR2TDP1LMNAATMCA12 | |
| SCHEMBL3516696 | 0.82 | HCAR2 (0.55) | HCAR2TDP1LMNAATMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |