Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135761 | 1.00 | HCAR2 (0.55) | HCAR2TSHRATMCA12AKR1B10 | |
| SCHEMBL8641565 | 0.89 | HCAR2 (0.52) | HCAR2TSHRATMCA12AKR1B10 | |
| SCHEMBL8641575 | 0.89 | HCAR2 (0.52) | HCAR2TSHRATMCA12AKR1B10 | |
| SCHEMBL3516591 | 0.84 | HCAR2 (0.62) | HCAR2TSHRATMCA12AKR1B10 | |
| SCHEMBL8416540 | 0.83 | TSHR (0.42) | HCAR2TSHRATMMAPTRAB9A | |
| SCHEMBL608166 | 0.82 | TSHR (0.64) | HCAR2TSHRATMMAPTRAB9A | |
| SCHEMBL1455147 | 0.82 | TSHR (0.64) | HCAR2TSHRATMMAPTRAB9A | |
| SCHEMBL216328 | 0.82 | TSHR (0.64) | HCAR2TSHRATMMAPTRAB9A | |
| SCHEMBL7538541 | 0.82 | HCAR2 (0.53) | HCAR2TSHRATMCA12AKR1B10 | |
| SCHEMBL7536969 | 0.82 | HCAR2 (0.53) | HCAR2TSHRATMCA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7061908-A | — | — | None | — | — | JP | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| JP-H0761908-A | NAIL COSMETIC | NIPPON OIL & FATS CO LTD | 1995-03-07 | — | — | JP | disclosed |