Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516773 | 1.00 | GRIK1 (0.38) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL10193601 | 1.00 | GRIK1 (0.38) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL305210 | 0.98 | GRIK1 (0.36) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL305208 | 0.98 | GRIK1 (0.36) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| Dimethylamine SCHEMBL3517020 | 0.93 | GRIK1 (0.34) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL5455564 | 0.85 | TP53 (0.41) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL5798580 | 0.85 | TP53 (0.41) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL305159 | 0.82 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL305161 | 0.82 | GRIK1 (0.33) | GRIK1GRIA4GRIK3GRIK5FFAR3 | |
| SCHEMBL15751550 | 0.82 | GRIK1 (0.33) | GRIK1GRIA4GRIK3GRIK5FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |