Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL3517020

CCC(C(=O)O)=C(C(=O)O)C(C)C.CNC

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GRIK1 P39086 1/20 0.34
▸ GRIA4 P48058 1/20 0.34
▸ GRIK3 Q13003 1/20 0.34
▸ GRIK5 Q16478 1/20 0.34
▸ FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10193601 0.93 GRIK1 (0.38) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL3516773 0.93 GRIK1 (0.38) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL3516778 0.93 GRIK1 (0.38) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL305210 0.91 GRIK1 (0.36) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL305208 0.91 GRIK1 (0.36) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL5455564 0.79 TP53 (0.41) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL5798580 0.79 TP53 (0.41) GRIK1GRIA4GRIK3GRIK5FFAR3
Dimethylamine SCHEMBL10973447 0.78 FFAR3 (0.44) GRIK1GRIA4GRIK3GRIK5FFAR3
SCHEMBL12026332 0.77 FNTA (0.38) GRIK1
SCHEMBL12026285 0.77 FNTA (0.38) GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 — — US disclosed
US-20100240855-A1 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2010-09-23 — — US disclosed