⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144594 | 0.79 | CLK4 (0.46) | — | |
| SCHEMBL407722 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL1569452 | 0.74 | CYP1A1 (0.35) | — | |
| SCHEMBL21630319 | 0.74 | PARP15 (0.42) | — | |
| SCHEMBL17514771 | 0.73 | EGLN2 (0.34) | — | |
| SCHEMBL767603 | 0.73 | — | — | |
| SCHEMBL184366 | 0.73 | — | — | |
| SCHEMBL289531 | 0.73 | — | — | |
| SCHEMBL407833 | 0.73 | — | — | |
| SCHEMBL1357341 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 708 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265702-A | Microbiocidal isonicotinamide derivatives | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| WO-2024010784-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| EP-4223753-A1 | AROYL SUBSTITUTED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2023-08-09 | — | — | EP | claimed |
| EP-3720858-B1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2023-06-07 | — | — | EP | claimed |
| CN-116234550-A | Aromatic formyl substituted tricyclic compound and preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2023089049-A2 | MICROBIOCIDAL ISONICOTINIC AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-25 | — | — | WO | claimed |
| US-20220396579-A1 | MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF HEART FAILURE AND DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2022-12-15 | — | — | US | claimed |
| EP-3807266-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2021-04-21 | — | — | EP | claimed |
| WO-2003093245-A1 | SULFONYLQUINOXALONE ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | claimed |
| WO-2003008412-A2 | HETERO-BICYCLIC CRF ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |
| WO-2003008414-A1 | CHEMICAL COMPOUNDS | SB PHARMCO PUERTO RICO INC. (PR) | 2003-01-30 | — | — | WO | claimed |
| EP-1053224-B1 | BIPHENYLSULFONYL CYANAMIDES, METHOD FOR THE PRODUCTION THEREOF AND THEIR UTILIZATION AS A MEDICAMENT | AVENTIS PHARMA GMBH (DE) | 2002-08-21 | — | — | EP | claimed |
| US-6369069-B1 | CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | claimed |
| EP-0086304-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS PESTICIDES AND PROCESSES FOR MAKING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-02 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0086916-A1 | Novel process for preparing heterocyclic compounds useful as pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-31 | — | — | EP | claimed |
| EP-0086917-A1 | Heterocyclic compounds useful as pesticides and processes for making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-31 | — | — | EP | claimed |
| EP-0086304-A1 | Heterocyclic compounds useful as pesticides and processes for making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-24 | — | — | EP | claimed |