⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407722 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL26610767 | 0.74 | PARP15 (0.42) | — | |
| SCHEMBL184366 | 0.73 | — | — | |
| SCHEMBL351688 | 0.73 | — | — | |
| SCHEMBL28407972 | 0.73 | — | — | |
| SCHEMBL289531 | 0.73 | — | — | |
| SCHEMBL1357341 | 0.73 | — | — | |
| SCHEMBL767603 | 0.73 | — | — | |
| SCHEMBL9659680 | 0.73 | — | — | |
| SCHEMBL27891335 | 0.72 | GSK3B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | claimed |
| US-20140378305-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2014-12-25 | — | — | US | claimed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | claimed |
| US-4104270-A | Process for the manufacture of aromatic phosphonates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-01 | — | — | US | claimed |
| CN-109180669-B | Iminothiadiazine dioxide derivatives and their use | 广东东阳光药业有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-109232468-B | Camphorsulfonic thiosemicarbazone thiazole compound, and preparation method and application thereof | 南京林业大学 | 2020-05-19 | — | — | CN | disclosed |
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| CN-106045921-A | SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | 勃林格殷格翰国际有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106045920-A | SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY | 勃林格殷格翰国际有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106008369-A | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 勃林格殷格翰国际有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105801571-A | Heterocyclic difluoromethylated oxirane compound and preparation method thereof | 上海大学 | 2016-07-27 | — | — | CN | disclosed |
| EP-2387569-B1 | HERBCIDES | SYNGENTA LTD (GB) | 2016-06-15 | — | — | EP | disclosed |
| CN-1070863-C | Phosphonic diester derivatives | OTSUKA PHARMA CO LTD (JP) | 2001-09-12 | — | — | CN | disclosed |
| EP-1115700-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AG (DE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017157-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| CN-1206419-A | Phosphonic acid diester derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-01-27 | — | — | CN | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5081112-A | Administering an aryl phosphonate carboxamide | OTSUKA PHARMACEUTICAL FACTORY INC. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4104270-A | Process for the manufacture of aromatic phosphonates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-01 | — | — | US | disclosed |