SCHEMBL3517295

SCHEMBL3517295

CC(C=O)OC(=O)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.39
ELANE P08246 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980890 0.81 PRKCA (0.39) PRKCAELANE
SCHEMBL2976271 0.81 PRKCA (0.39) PRKCAELANE
SCHEMBL23466983 0.79
SCHEMBL16077777 0.76 PRKCA (0.36) PRKCAELANE
SCHEMBL16077780 0.76 TSHR (0.41) PRKCA
SCHEMBL8211801 0.74 PRKCA (0.45) PRKCAELANE
SCHEMBL23581471 0.74 TSHR (0.35)
SCHEMBL2478389 0.74 TSHR (0.48) PRKCAELANE
SCHEMBL3895108 0.73 PRKCA (0.37) PRKCA
SCHEMBL23581473 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2219448-A1 THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS Myriad Pharmaceuticals, Inc. (US) 2010-08-25 EP disclosed
WO-2009065035-A1 THERAPEUTIC COMPOUNDS AND THEIR USE IN TREATING DISEASES AND DISORDERS MYRIAD GENETICS, INC. (US) 2009-05-22 WO disclosed