Phosphoric Acid

Phosphoric Acid

SCHEMBL3517608

O=C1CCN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)N1.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.60

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CDA P32320 10/20 0.60
MAPT P10636 1/20 0.42
SLC28A1 O00337 1/20 0.41
SLC28A2 O43868 1/20 0.41
SLC29A1 Q99808 1/20 0.41
SLC28A3 Q9HAS3 1/20 0.41
PYGM P11217 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30241991 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL40762 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL11757296 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18512842 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18512836 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL18503564 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL6015184 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL399314 0.94 CDA (0.66) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL8772894 0.88 CDA (0.59) CDAMAPTSLC28A1SLC28A2SLC29A1
SCHEMBL31685779 0.84 CDA (0.50) CDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100317005-A1 Modified Nucleotides and Methods for Making and Use Same Life Technologies Corporation (US) 2010-12-16 US claimed