⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041320 | 1.00 | — | — | |
| Water SCHEMBL458509 | 0.97 | — | — | |
| SCHEMBL28375260 | 0.97 | — | — | |
| SCHEMBL4985 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL21465084 | 0.94 | — | — | |
| SCHEMBL5602 | 0.89 | — | — | |
| SCHEMBL12971467 | 0.84 | — | — | |
| Tetrahydrofuran SCHEMBL28437844 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL7766444 | 0.82 | — | — | |
| SCHEMBL4960 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2010 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059801-A | Synthesis method of Marbalol Sha Wei side chain intermediate | 重庆圣华曦药业股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| US-12479819-B2 | Method and compound useful in preparation of orexin-2 receptor antagonist, and lemborexant having few impurities | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-11-25 | — | — | US | claimed |
| EP-4613745-A2 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | Gilead Sciences, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| EP-4192809-B1 | PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF SIPONIMOD | OLON SPA (IT) | 2025-09-03 | — | — | EP | claimed |
| CN-119176812-B | Method for preparing triazolo [1,5-a ] pyrazine-3-carboxylic acid and application thereof | 苏州盛迪亚生物医药有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119930381-A | Synthesis method of Z-configuration chiral olefin | 深圳连续制药科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119798080-A | Preparation method of (R) -5- ([ 1,1' -biphenyl ] -4-yl) -2-methyl-4-oxopentanoic acid calcium salt | 杭州科巢生物科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-116496150-B | Preparation method of 2, 7-dimethyl-2, 4, 6-octatriene-1, 8-dialdehyde | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-119462520-A | Preparation method of substituted benzoate derivative | 上海皓元医药股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| US-20030114693-A1 | Method of preparing optically pure (R) - or (S) - tetrahydrofuranyl ketone | SK CORPORATION | 2003-06-19 | — | — | US | claimed |
| EP-1318148-A1 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK Corporation (KR) | 2003-06-11 | — | — | EP | claimed |
| US-6479661-B1 | Method for symmetrically and asymmetrically disubstituting carboxylic acid amides with organotitanates and grignard reagents | MERCK PATENT GESELLSCHAFT (DE) | 2002-11-12 | — | — | US | claimed |
| WO-2002053607-A1 | A METHOD FOR PRODUCING ETHYLENE HOMO- AND COPOLYMER | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2002-07-11 | — | — | WO | claimed |
| US-5451693-A | Water repellant for treating surfaces of construction materials | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-09-19 | — | — | US | claimed |
| EP-0643064-A1 | Tert-butyl cycloalkyl dialkoxysilane compounds and method for preparing same | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-03-15 | — | — | EP | claimed |
| US-4958041-A | FROM TETRAALKOXYSILANE OR MONOORGANOTRIALKOXYSILANE AND GRIGNARD | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-18 | — | — | US | claimed |
| EP-0144729-B1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-11-08 | — | — | EP | claimed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | claimed |
| US-4113758-A | Process for preparing organotin halides | ALBRIGHT & WILSON LTD. (GB) | 1978-09-12 | — | — | US | claimed |