⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524010 | 0.82 | PRKD3 (0.59) | — | |
| SCHEMBL3520557 | 0.82 | BRAF (0.45) | — | |
| SCHEMBL3520134 | 0.82 | CSNK1E (0.48) | — | |
| SCHEMBL14561793 | 0.79 | — | — | |
| SCHEMBL4471049 | 0.79 | — | — | |
| SCHEMBL14560997 | 0.78 | — | — | |
| SCHEMBL14600037 | 0.78 | CSNK1E (0.48) | — | |
| SCHEMBL1730877 | 0.78 | PRKD3 (0.58) | — | |
| SCHEMBL3523752 | 0.78 | PRKD3 (0.56) | — | |
| SCHEMBL3524969 | 0.78 | CSNK1E (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| EP-1928237-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | Abbott Laboratories (US) | 2008-06-11 | — | — | EP | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
| WO-2007028051-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |