SCHEMBL35210259

SCHEMBL35210259

C=CC(=O)Nc1cc(Nc2cc(Nc3cc(OC)c(Cl)cc3Cl)ncn2)c(OC)cc1OCCN1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EGFR P00533 10/20 0.56
KDR P35968 5/20 0.53
FGFR1 P11362 5/20 0.46
CYP3A4 P08684 1/20 0.44
FGFR3 P22607 1/20 0.44
FGFR4 P22455 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548911 1.00 EGFR (0.56) EGFRKDRFGFR1CYP3A4FGFR3
SCHEMBL19089422 0.99 EGFR (0.55) EGFRKDRFGFR1CYP3A4FGFR3
SCHEMBL19089427 0.96 EGFR (0.52) EGFRKDRFGFR1
SCHEMBL19089420 0.94 FGFR1 (0.52) EGFRKDRFGFR1
SCHEMBL35210289 0.94 FGFR1 (0.52) EGFRKDRFGFR1
SCHEMBL20655722 0.93 EGFR (0.54) EGFRKDRFGFR1
SCHEMBL19089421 0.90 FGFR1 (0.55) EGFRKDRFGFR1
SCHEMBL20548915 0.90 EGFR (0.56) EGFRKDRFGFR1CYP3A4FGFR3
SCHEMBL35210316 0.90 EGFR (0.56) EGFRKDRFGFR1CYP3A4FGFR3
SCHEMBL20548767 0.87 FGFR1 (0.47) EGFRKDRFGFR1FGFR3FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP claimed
EP-3398939-B1 ACRYLANILIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATIONS THEREOF IN PHARMACY ANCUREALL PHARMACEUTICAL SHANGHAI CO LTD (CN) 2026-05-06 EP disclosed